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» LymeNet Flash » Questions and Discussion » Medical Questions » Grapefruit seed extract question

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Author Topic: Grapefruit seed extract question
Tiramisu
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I'm currently on Zith, and also Diflucan every 3 days.

I'm looking into GSE to try topically for these itchy bumps on my scalp. I would also consider taking orally.

I'm confused about mixing Grapefruit with certain meds. Here are my questions:

Should I avoid GSE completely while on Diflucan?

Can it be spaced 2 hrs apart, like probiotics?

What abx do you need to avoid with GSE?

What about using it topically?

Thanks in advance!

Posts: 175 | From SW PA | Registered: Mar 2008  |  IP: Logged | Report this post to a Moderator
groovy2
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Hi Tiramisu -

GSE is Very strong --make sure to dilute with water
if you are going to use on skin--

Dont use with Any of the Cyclines ABX
Doxi or Mino ect--jay--

Posts: 2999 | From Austin tx USA | Registered: Oct 2004  |  IP: Logged | Report this post to a Moderator
Judy G.
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My llmd has me on citricidal (Grapefruit seed extract) along with minocycline and occasional Diflucan when the yeast gets too much.

I don't take it at the same time as the abx after reading about it on this site, but no problems with taking it like this, and I have taken it for several months.

--------------------
Judy G.

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peacemama
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I take with Mino and used to take with Doxy, but not close together. Had a really bad reaction -- drug herb interaction taking it close together.

I worked up to 15 drops 2 times a day in water.

Yes, space as far away from probiotics as you can. . .I was prescribed Diflucan and my LLMD has me on GSE. Haven't taken it yet though.

Posts: 564 | From Tick Hell | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
pamoisondelune
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What drug interactions? What happens??

I take Minocycline empty stomach, then GSE with meals 2 hours apart from the empty stomach pills.

I never knew thay aren't supposed to be taken together--- what happens?

I take 15 drops GSE 3x/day, in tomato juice.

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Peedie
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I have used it with my hair shampoo - three drops to a palm full of shampoo for itchy scalp. I've only done this for the four last shampoos - but have not noticed any difference in itching. My hair is really soft tho ---?

I tend to get the little bumps on shoulders and chest. Was using the shampoo mixures there also - but no improvement.

I'd really like to find something for the itching and little bumps also Tiramisu. Let me know if you find anything.

-p

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Abxnomore
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For bumps on your body you may want to try putting soap and some tea tree oil on a loofah and use it frequently. Skin brushing or exfoliating is very
beneficial for detoxing and the tea tree oil is good for fungus and weird stuff.

Perhaps a shampoo that contains tea tree oil may help on the scalp as well.

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peacemama
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It was more intense than my typical herx. I shook like a drug addict in withdrawl and I threw up.

I took them almost together. I started too strong with the GSE (10 drops) and then took them within 1/2 an hour of each other (I wasn't paying attention).

I have had NO trouble with the GSE and the mino, and I space them 2 hours or a little less. Doxy was when I had the reaction and it was awful.

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Ocean
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I didn't take GSE with any meds as I didn't know I had Lyme, was just sick and tired of being sick and tired.

I had taken it years before, so I wanted to try a high dose. Took 60 drops in one day (20 drops, 3 X/day). When I woke up the next day I felt like someone had beaten me with a baseball bat. My arms, back, legs and feet were soooo sore. It lasted for a few days.

So start out slowly so you don't end up feeling like crap right off the bat!

See... aren't you glad I make mistakes FOR you, so you don't have to???!


Ocean

--------------------
http://www.healingfromlymedisease.blogspot.com/

Sick since 1996...Diagnosed 10/2008

IgM:23-25 IND, 31+++, 39 IND, 41 +++
IgG: 31 IND, 41++, 58+

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Tiramisu
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Thanks everyone for the great input!

There's conflicting info online about which meds have bad interactions with grapefruit juice that you DRINK. Some of the lists do not include any abx. But if anyone's interested, see this article:

http://www.eurekalert.org/pub_releases/2005-01/uorm-gja011705.php

My llmd said to avoid grapefruit seed extract while on Diflucan because they both are metabolized by the CYP450A pathway. I guess it can overtax the liver, maybe. He didn't say what would happen.

Anyway, a pharmacist told me to just space grapefruit juice 2 hours from the Diflucan. (didn't bother telling him I plan to take the GSE instead of drinking the juice)

Another pharmacist said GSE applied topically should give no adverse reactions.

I plan to dilute it and apply to scalp with a mini spray bottle, like a small hair spray bottle. But the shampoo method sounds good too.

I believe in starting everything slowly...60 drops in one day, wow! What is a safe dose to start with for oral GSE?

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Tiramisu
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What is a safe dose of oral GSE to start with? (Liquid drops)
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Peedie
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I believe it is btw. 8-12 drops and always diluted in a drink - like juice. Your GSE should have come with instructions. Mine were kinda hidden -

I had to peal back the plastic label on the bottle. All of the sudden there were many many uses for GSE - including the 3 drops in a palm of shampoo method.

I started with 8 drops in juice and worked up to 12 by the end of the week. That's the dose I'm comfortable with. I'm on break from it while herxing on abx.

-p

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psano2
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Peedie, do you take it just once a day or more often?
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psano2
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pamoisondelune,

How long have you been taking 15 drops 3x/day? I'm only taking 8-9 drops at bedtime, and it's knocking me out. If I took it 3x/day, I wouldn't be able to function.

I'd think if I were able to get up to the dose you're on, I'd pretty much be cured. How are you feeling?

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asus
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GSE kicked my butt, made me way more tired and "dull" and felt pretty sick (sick-er is I guess the word). It really irritated my GI tract and made me very constapated for a couple weeks to the point of needing a laxative.

I took only 10 drops in water for a couple days.

There is some controversy about GSE (grapefruit extract - not grape seed extract) in that either its contaminated by industrial strength antiseptic "benzalkonium chloride" or somehow in the process of making GSE, it takes on characteristics identical to this substance.

I seem to recall this study being done by the USDA and being replicated.

So it might well be that its "antibiotic" properties are from a senthetic chemical which may not be all that great to ingest...

I'd say be careful with it.

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psano2
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I called Nutribiotics about the reports of benzalkonium chloride in GSE and here is what they said in an email:

"Newsgroups, email groups, and web sites have received postings to the effect that GSE contains triclosan, benzelthonium chloride, or methyl paraben. The reason is that GSE is very similar in molecular weight to both benzelthonium chloride and triclosan, both of which are effective disinfectants, but are toxic to human and animal life. Some tests for BC, triclosan, and methyl paraben come up positive (which is more correctly called a "false positive") and the same is happening for triclosan.

Meanwhile, Citricidal (the brand of GSE NutriBiotic uses) has been tested for the presence of these toxins by independent labs, and has been proven clean. (Ex: Weston Gulf Coast Laboratories, Inc., University Park, IL, test completed in March of 1992. Tested for heavy metals, Cyanides, Pesticides and PCBs and Benzalkonium Chloride. Results: None Detected.) In fact, the accusations about triclosan (used in many dish and hand soaps in the US) became so frequent a few years ago, that Citricidal began specifically testing each batch of GSE for its absence, and providing a Certificate of Analysis to that effect.

The truth is, Citricidal is not only effective, it has been in use for many years (20+). If these allegations had any validity, there certainly would be a history of complaints and judgments against the product, and it would have been removed from the market many years ago. The US FDA made inspections of the Nutribiotic manufacturing facility back in the 1990's and found no chemical preservatives; and the formula is the same today. Such rumors are false, and are not a threat to those armed with accurate information. The reports are certainly bothersome, but they have produced "false positives", not accurate profiles. The vast body of evidence from many years of use by thousands of satisfied consumers, doctors, manufacturers, and veterinarians, speaks most loudly against such reports. Citricidal and NutriBiotic GSE are proven, safe, and effective products.

If you have any further questions, please call us at 800-225-4345. Thank you."

Posts: 975 | From California | Registered: Apr 2007  |  IP: Logged | Report this post to a Moderator
   

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