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» LymeNet Flash » Questions and Discussion » Medical Questions » Igenex test results..need input

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Author Topic: Igenex test results..need input
Surruh
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Hi everyone
So here are my results

IgM Western Blot (positive for Igenex)
**31++
**41++
**83-93 IND

IGG
**41IND

My llmd is keeping me on antimicrobials and some other supplements right now and he is going to consult with Dr. H on my results.

Does anyone have any thoughts on this? Is it positive enough?

Thanks
-Sarah

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nenet
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You do not have to worry about whether your test is "positive enough." A third of true, DNA-proven Lyme cases are missed by current testing - meaning that there is a huge number of false negative test results. The reasons for this are many.

"Lyme disease is diagnosed based on symptoms, objective physical findings (such as erythema migrans, facial palsy, or arthritis), and a history of possible exposure to infected ticks."

In other words, Lyme disease diagnosis is not based on tests, but on clinical findings and judgement.

Straight from the horse's mouth (the CDC)

http://www.cdc.gov/ncidod/dvbid/lyme/ld_humandisease_diagnosis.htm

You also need to have your doctor rule out other possible causes of your symptoms, just as in any other case, unless someone has a Lyme rash.

--------------------
Dr. C's Western Blot Explanation

Lymenet Success Stories

ILADS Treatment Guidelines

Medical & Scientific Literature on Lyme

"Long-Term Antibiotic Therapy Improves Persistent Symptoms Associated with Lyme Disease"

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Keebler
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-
Others will be along with specific comments that my brain cannot come up with right now.

I assume you are experiencing symptoms. Remember that those need to be figured into the mix just as much (or more) than whether you have the exact lottery number matches for the CDC. You do not need to match the CDC criteria.

I am glad to see you have a LLMD, and I assume that he is ILADS educated if he is going to discuss this with another ILADS-member LLMD.

In the meantime:
-------------

Dr C's Western Blot explanation is discussed here:

http://flash.lymenet.org/ubb/ultimatebb.php?ubb=get_topic;f=1;t=042077

"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years.

Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.

But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies.

Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result.

Response to antibiotics is the same if either is positive, or both. Some antibodies against the borrelia are given more significance if they are IgG versus IgM, or vice versa.

Since this is a chronic persistent infection, this does not make a lot of sense to me. A newly formed Borrelia burgdorferi should have the same antigen parts as the previous bacteria that produced it.

But anyway, from my clinical experience, these borrelia associated bands usually predict a clinical change in symptoms with antibiotics, regardless of whether they are IgG or IgM."
-

[ 10-10-2009, 08:16 PM: Message edited by: Keebler ]

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Keebler
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-
I was composing while nenet was posting. So, some of my reply echo's his/hers.

Did you ever have a rash after tick-bite? That does not always happen but if you had (especially) the classic bulls-eye rash, that is clearly indicative of lyme. Other kinds of rashes are not uncommon, though, most often there is no rash.


As nenet said, other things need to be ruled out - or considered - for clearer picture. Even with lyme, you could also have other tick-borne disease (TBD).

Be sure to be assessed for those, too. Babesia, etc. . . .

www.igenex.com

IGENEX

====================

In addition to the usual coinfections from ticks (such as babesia, bartonella, ehrlichia, RMSF, etc.), there are some other chronic stealth infections that an excellent LLMD should know about:


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=069911#000000

TIMACA #6911 posted 03 August, 2008

I would encourage EVERY person who has received a lyme diagnosis to get the following tests. . . .

- at link.
-

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Lymetoo
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If Igenex says it's positive, I would say it's positive.

Band 83-93 is the DNA of the Bb.

--------------------
--Lymetutu--
Opinions, not medical advice!

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Pinelady
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I agree, the 31kda is the genetic material they used to make the failed vaccine. Good Luck in your treatment and many are here to help should you need it. Prayers for a easy road to wellness.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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timaca
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Hi Sarah~
I would not jump at a lyme diagnosis. You have band 41, which pretty much everyone has. You have band 31, which may actually indicate a viral infection. That's all the bands you have...not near enough to consider lyme as a strong possibility. You also don't have any bands on IgG, and if you've been sick for awhile, you should have some bands on IgG.

Here's some things to consider: (1) Depending on how long ago your Igenex test was done, ask them to run a band 30/31 confirmation test.

(2) Make sure your doctor has ruled out all other obvious causes of your health problems (thyroid, anemia, Vit D deficiency, etc).

(3) Get tested for a lot of other pathogens that can give the same symptoms as lyme. For example, HHV-6, EBV, Cpn, enterovirus, etc. Do a search on lymenet using my member number and the words "viral testing" and you'll get some info.

Based on those results, treat the most obvious. Lyme simply is not the most obvious based on your test results. And if you think you have lyme, get tested at SUNY Stonybrook and MDL lab too before undergoing treatment.

You want the right answer, not any answer.

Best, Timaca

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nenet
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quote:
Originally posted by Lymetoo:
If Igenex says it's positive, I would say it's positive.

Band 83-93 is the DNA of the Bb.

Lymetoo makes a good point here. Before I learned more about the disease and testing weaknesses, I would have doubted my Lyme diagnosis if not for my band 39 on the IgM (which is species specific to Lyme). Even so, I have responded to treatment for Lyme over the last 16 months.

Testing is USELESS if it is a negative result, even according to the CDC, and Lyme diagnosis is based on exclusion of other factors, patient history, and symptoms, both subjective and objective.

Please do not stop treating for Lyme if you have been diagnosed by an LLMD and are undergoing or about to start treatment. A good LLMD will either voluntarily test you for other infections, or will be responsive to your requests for more testing.

Are you seeing an ILADS-based LLMD?

--------------------
Dr. C's Western Blot Explanation

Lymenet Success Stories

ILADS Treatment Guidelines

Medical & Scientific Literature on Lyme

"Long-Term Antibiotic Therapy Improves Persistent Symptoms Associated with Lyme Disease"

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Hoosiers51
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Timaca said: "You also don't have any bands on IgG, and if you've been sick for awhile, you should have some bands on IgG."

I would have to disagree with that statement.

Many times Lyme patients do not show many IgG bands until they start to recover from illness, according to doctors with experience treating chronic Lyme.

Since band 31 can also be caused by a virus, I would recommend Igenex's band 31 confirmation test.

Also, you may have more bands show up after taking some antibiotics to draw the bacteria out.

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sutherngrl
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I also disagree with Timaca about the IGG bands. What Hoosiers says is very right.

Also Lyme Disease is a clinical diagnosis! Don't know why so many here still don't get that.

I have been very ill for 3 and a half years and the only bands that have showed up for me is IGM bands 41 and 23. 23 only after over a year of treatment. Thank goodness I have a good LLMD that knows LD is a clinical diagnosis.

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timaca
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People with CMV and EBV (among other things) can have a false positive IgM WB for lyme. See:
http://www.springerlink.com/content/631rx51r28577w46/

Rheumatoid conditions and viruses may give a false positive IgM result:
http://www.igenex.com/lymeset2.htm

One must rule out these conditions before one jumps at a lyme diagnosis.

Here is a good testing diagram which illustrates that if one has been ill longer than 8 weeks and has no IgG response, you really need to consider another diagnosis.

http://www.arupconsult.com/Algorithms/LymeDz.pdf

Finally here is an article where a boy had VZV, not lyme, even though his IgM was positive for lyme. He never had positive IgG antibodies for lyme...something doctors look for if one really has lyme. They should show up...if one has lyme.

http://resources.metapress.com/pdf-preview.axd?code=7qane55dg89qrh4b&size=largest

Just trying to make sure you rule out other, more likely causes for your illness....especially if you have been ill longer than 8 weeks.

Best, Timaca

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coltman
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quote:
Originally posted by sutherngrl:

Also Lyme Disease is a clinical diagnosis! Don't know why so many here still don't get that.

Because there are so many other things which can cause symptoms of "clinically diagnosed Lyme". Majority of chronic bacterial/viral/fungal infections fit the bill.

quote:

I have been very ill for 3 and a half years and the only bands that have showed up for me is IGM bands 41 and 23. 23 only after over a year of treatment. Thank goodness I have a good LLMD that knows LD is a clinical diagnosis.

23 is lyme specific though -ospC surface protein.

Anyways imho if you strongly suspect bacterial infections you should treat with combo abx .There is no real difference whether you treat CPN ,lyme or tuberculosis

Viruses are another story though

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Marz
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If a person still tests positive IgM after 18 months on antibiotics and being sick for years, does that mean they do have lyme or could it still be EBV?

I had IND band 31 plus other + bands both before and after treatment.

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Lymetoo
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According to Dr C of MO, more chronic Lyme patients are positive on the IgM than on the IgG.

He also explains why. Check it out!

http://tinyurl.com/ffn3x

--------------------
--Lymetutu--
Opinions, not medical advice!

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Pinelady
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The confirmation test is not written in stone.


Like the WB if you do have a virus also it can be

skewed. Case in point. I have a 31+++ kDa with a

neg confirmation test. I have since found out I

also have a virus. It should not be used as fool proof.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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timaca
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If you read the first article I posted, it states: "Approximately 60% of the lyme IgM EIA positive sera from CMV and infectious mononucleus patients reacted in the WB test with one of the two proteins considered highly specific, mainly OspC." (That's band 23) To read it for yourself, click on "Full text preview--large". It's at the bottom of the left hand column. Just because someone tests positive to one or two lyme specific bands does not mean that they have lyme. You have to explore what could be causing that result, and make the best diagnosis. Not say it's lyme, for it may not be.

Marz~ Have you ever had any IgG positive bands? If so, lots or a few? (IND don't count). Which labs? Are you better after antibiotic treatment? What are your EBV titers? For info on EBV see:
http://hhv6foundation.proboards.com/index.cgi?board=testing&action=display&thread=182 (You will need to sign in to read the post)

Basically, run lots of tests, and treat what is most obviously wrong. Even if you had lyme, viruses could be a problem.

I wonder if Dr C has checked his patients for viruses....
Seriously, how does he know that they have "chronic lyme" and only chronic lyme if he has not checked his patients for EBV, HHV-6, HSV1, enterovirus or Cpn? You have to run all the tests and treat what is most obviously wrong. (I have all the pathogens that I mentioned above)

Just trying to make the point...test for lots of things. Treat what looks to be the most likely problem(s). One or two bands on a WB is not deemed a likely problem, especially if your haven't ruled out other causes.

Best, Timaca

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seekhelp
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Nope, not at all. I don't this LLMD believes much in anti-viral treatment, but is not opposed to it. All viruses are assumed to become non-factors with successful Abx treatment.

My problem is if you've been treating Lyme for 2, 3, 5 years w/o success, mabe it's not a 'non-factor' after all. [Smile]

Going back to your original article, that is VERY disturbing to me that LLMDs don't mention EBV cross-reacts on the 23-25 band. Wow. wow, wow. Thst band is really what I've been basing my Lyme diagnosis on. The 41 and 58 dont' mean much to me. Do LLMDs not know about this article?

quote:
Originally posted by timaca:


I wonder if Dr C has checked his patients for viruses....
Seriously, how does he know that they have "chronic lyme" and only chronic lyme if h e has not checked his patients for EBV, HHV-6, HSV1, enterovirus or Cpn? You have to run all the tests and treat what is most obviously wrong. (I have all the pathogens that I mentioned above)

Best, Timaca


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timaca
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Hi Seekhelp~
What is interesting in that article is the other band that was cross-reacting besides OspC was band 39. So, again, having reactions on one or two bands, even highly specific lyme bands, may not mean you have lyme.

The doctor, who I am working with, who is an ID doctor and who is awesome...we discussed this. That is why the CDC came up with 5 out of 10 bands on the IgG WB for a positive lyme diagnosis. If you get one or two bands, it likely isn't lyme. The more bands you have, the more likely you have lyme. Basing your diagnosis on symptoms alone, or one or two lyme specific bands just is not a good idea.

It is a good idea to check for all these other pathogens, for they can be causing problems too. Even if you are sure you have lyme.

And the viruses won't go away if you treat the lyme. They are wicked pathogens that need treatment too.

Best, Timaca

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Lymetoo
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Timaca, I know he checked me for HHV6 and EBV.

--------------------
--Lymetutu--
Opinions, not medical advice!

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coltman
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quote:
Originally posted by seekhelp:
Going back to your original article, that is VERY disturbing to me that LLMDs don't mention EBV cross-reacts on the 23-25 band. Wow. wow, wow.


What article? EBV crossreacts on 23?!? A link please?

Also how do you treat EBV? Acyclovir?


quote:
Cpn?
CPN treatment is antibacterial treatment though. Almost exact same as lyme
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Lemon-Lyme
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The thing about EBV cross-reacting, at least according to the info I received from Igenex, is only an EBV IGM positive could possibly affect the WB IGM result (not an EBV IGG positive). So assuming your doctor tests you for viruses beforehand, and if you don't actively have mono, the odds are a positive band 31 is an actual positive band.

Virus testing before the WB is probably a cheaper way to go than the confirmation test too, since insurance will usually pay for those.

I both agree and disagree with timaca. You don't have to have lots of WB IGG bands to have Lyme. My test results were similar to Surruh -- IGM positive, but only like 2 bands IGG. And years before that (like 8 years ago) I had a WB with no IGM bands, but several IGG bands (3-4, if I remember right). So apparently some IGG bands vanished on me, or the tests were just too inaccurate a measure to diagnose Lyme by.

Other diseases should be ruled out, but if they are, and your symptoms match Lyme and you are diagnosed with Lyme by a good doctor, it seems prudent to treat regardless what your WB says. There is also the issue of co-infections -- if you test positive for co-infections, it's also a big clue as to Lyme, regardless of how many WB bands show up. Co-infections are sort of a red flag saying: 'Sickly tick bit me'.

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Pinelady
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I am sorry I disagree. IND's do count. I think if they have to look with a magnifying glass to see it- it counts. And I am glad they are looking when others aren't.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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ping
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quote:
Originally posted by Lymetoo:
According to Dr C of MO, more chronic Lyme patients are positive on the IgM than on the IgG.

He also explains why. Check it out!

http://tinyurl.com/ffn3x

Lymetoo - I don't think Dr. C meant this "across the board" because my IGG was flaming hot, while my IGM had only 2 IND.

Although we understand that Borrelia is a clinical diagnosis, let's face it, most docs still want to see a CDC positive test.

Surruh - From the results of your test, you have Lyme, regardless of the EBV, etc., etc. You're positive for Lyme. If it's "CDC Positive", as Lymetoo says, it should state that on the test.

ping
"We are more than containers for Lyme"

--------------------
ping
"We are more than containers for Lyme"

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timaca
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Coltman~ The article I'm referring to is the first link in my second post.

Different antivirals are used for EBV. I think valtrex, acyclovir and famvir may all be used.

Lemon-lyme, you make a good point...and one I was also going to bring up, in that the articles that I mentioned, were all (I think anyway, I'd have to go back and look) acute cases of being ill. Not chronic cases. However, no studies have been done on chronic illness and how their blood tests out. (Although, since my doctor sees a lot of chronically ill patients, he has seen a lot of their blood tests...just no studies have been done).

In my case, I had lots of bands on WBs from both Stonybrook and Igenex. Did I have lyme? Maybe. Maybe not. Do I have a bacterial infection? Yes. Most likely that is Cpn since I am as high as the lab measures as far as IgG and IgA antibodies. Maybe I have lyme (lots of people on lymenet would say I do). I'm not as convinced of that.

I do have LOTS of viruses to deal with: HHV-6, EBV, enterovirus, VZV and HSV1. I would not have known about these if I had not tested for them.

Remember, viral symptom and lyme symptoms are the same. You can't tell the difference. So, if you have one or two bands on the western blot, and assume it's lyme based on symptoms, you may be barking up the wrong tree. Get tested for the viruses too and treat what looks most obviously wrong.

Pinelady~ Dr. F at Columbia tosses out the IND bands from Igenex. He knows more about lyme than most anyone in this country. That's where I got my decision to do the same.

My advice...test for a lot of things, treat what is most obviously wrong. That will give all of us the best chance of getting well.

I've had the best 4 1/2 months in the last 6 years. That is because I've treated the viruses too.

Best, Timaca

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seekhelp
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Come to think of it, I had tons of labs done before I saw my LLMDs so maybe there was no need to re-run snd it's different for patients that didn't undergo the testing first.

The co-infection aspect was exactly what I was thinking about too. Havng positive labs there makes Lyme much more likely. Unfortunately I don't have that piece of mind. Mine are so borderline it could go either way.

Timaca, I wonder if that 23-25 band cross-reactsd with EBV-EA antibodies and not just IgM? I read no one who has a recurrent EBV infection ever tests positive for IgM. It's a one time positive, unlike many other acute infections.

We all have our beliefs. I choose to ignore the IND bands on my WB. It makes no difference in the big picture really. The three questions always are the same:

- Does something else cross-react with bands 31 and 41...answer yes. Now possibly 23-25?

- Is Igenex completely reliable given all other labs fail to show anything? Answer....pretty likely based on stories I hear.

- Is Igenex picking up STARI strain. answer: I sure hope that's the reason because it's the only reasonable one. Any other possibilities start to get more upsetting.`

- Oh question / issue #4: Is Lyme actually the cause of my medical issues? When hearing Igenex and some LLMDs say 90%+ of the general population has positive Lyme titers, this is a good concern. [Smile]

Response to Abx treatment is very meaningful to me too.

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springshowers
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Timaca

Have you seen people who have the Flu and on Tamiflu see an improvement in overall symptoms?

?? I was thinking because it is an anti viral ? Maybe? But not sure if it might target only specifically flu.

Also. I have a suggestion. If anyone sees a homeopathic doc or has access to any energy or frequency testing through any doctor. It is a great tool.

I just got tested and the doctor added in all the Lyme and co infections and added in all the viruses to see where my loads were.

Great tool in my opinion. WE are to check again in a couple weeks to compare.

I agree that you have to treat those Viruses !! and as well as Fungals.. And the Protozoans as well as the bacterials.

I find the 4 way attack works well for me. Always keeping on board something to address all 4.

That is how I self treated for a couple years and then now after a few years my doctor is saying he is finding many patients doing well when he gives them one of each of these at the least and in various combinations depending on the test results and symptoms.

I find I can tell when the viruses are having what I call joy ride ... as compared to the other infections.
The pain is different and I have just learned through the years how to identify it.. I my case anyway... I can tell somewhat.. Not exactly of course...

But my doctor has listened to me on this and when adjusting in the direction or making changes per what I say I think is going on .. Works out and I respond accordingly.

Pretty cool... when I can do that..

Of course not all the time : )

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Lymetoo
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Ping.. WEll, he's talking about percentages here. Of course many have positive IgG's but more people have positive IgM's than IgG's.

--------------------
--Lymetutu--
Opinions, not medical advice!

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joahsark
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I don't get it. Almost all the posts here say the complete opposite of what is posted just about everywhere else on this board.

"IND"s don't count???? What happened to the posting and re-posting of doc stating they're just like "light fingerprints" they are still there.

Lyme specific bands don't neccesarily mean lyme?

Two bands on Igenex doesn't mean anything even though they say it does?

I thought "clinical diagnosis" was most important. This thread changes just about everything important I'd thought you all were teaching me.

Is it just band 31 you're talking about? What about lyme-specific band 34?

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Lymetoo
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Some people posting here are NOT Lyme patients.

Yes, IND's are important!! They are weak positives.

--------------------
--Lymetutu--
Opinions, not medical advice!

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timaca
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Springshowers~ I don't know anyone on Tamiflu.

Joahsark~ Get tested for lots of things. Treat the most obviously wrong.

Lymetoo~ I was diagnosed with "probable" lyme by Dr. F at Columbia. I was treated for lyme by many years by a well respected LLMD, who I love very much. Whether I had lyme or not, who really knows? I do still have a bacterial infection and lots of viral infections.

Had I not treated the viruses AND my bacterial problem I would not have made the progress I've made.

Again, don't jump at any diagnosis, lyme or viral or otherwise. Get lots of tests run. Learn about what you are getting tested for. Treat the most obviously wrong....be it lyme or viral. Don't treat the maybes. You could be barking up the wrong tree if you do.

Best, Timaca

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coltman
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quote:
Originally posted by joahsark:
I don't get it. Almost all the posts here say the complete opposite of what is posted just about everywhere else on this board.


Well I think decisions that "all my symptoms are caused by lyme " needs a very careful consideration of other things . It is imho important to test for other things too


quote:

Lyme specific bands don't neccesarily mean lyme?

Two bands on Igenex doesn't mean anything even though they say it does?

Certain bands are speculated to be cross reactive. I dunno how much probability and didnt not research much into it, but I believe in this possibility - bacteria and viruses mutate and sometimes grab dna from other bacteria ,viruses (and sometimes our own)


Anyways having said all that and mulling over the issue one more time today (I got my own igenex results today!) I am leaning towards "gateway" theory . BB and/or CPN (which I am positive for too) suppress immmune system and cause all kind of other dormant viruses and bacteria to multiply as well.

Those bugs collectively cause all kinds of damage and destruction resulting in symptoms.

Treatment wise I think starting with anti bacterial make sense and if one get positive virus titers it seems to make sense too look at antivirals real close(aside of acyclovir familiy though antivirals have really nasty side effects profile)

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Lemon-Lyme
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That immune theory is actually a pretty good one. A person's immune system is generally out of whack due to lyme, which would explain why viruses come out of hiding and start to cause problems.

Now, the question which can be confusing for some people is are their symptoms due to viruses or Lyme? And then they wonder if they have Lyme at all.

I suppose the only way to know is to simply treat. Treat viral infections (if you test positive for viruses), and unless 100% cured, then treat Lyme. Or do it the other way around. An antibiotic challenge (either you herx, or get better, but you should get some response eventually) is probably the only way to determine if a person has Lyme, and even then, it's not exactly a full proof way to test.

Relying on the WB solely is a pretty crummy way to diagnose the disease. Testing is simply too inaccurate. It is still a clinical diagnosis, and good docs simply use blood tests as additional evidence. Exceptions would be PCR testing, or if a person had like 10+ bands + coinfections... that would be a good marker for Lyme. Shame they haven't improved PCR testing, as it would be the one test that is definite.

I personally think co-infections are a good marker, and wonder why they aren't used more often by non-LLMD docs as a testing method sometimes. If a person has two or more co-infections, I'd say the odds are that person has Lyme. Actually, if a person has one co-infection, it's pretty good evidence.

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Lymetoo
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Timaca.. Just keep in mind that what you say is often very confusing for those newly diagnosed with Lyme. I remember being very confused myself when first dxd.

I would hate for someone to stop treatment because they suddenly think their test results mean they don't have Lyme .. WHEN THEY DO.

Please keep that in mind when you post here. Thanks.

--------------------
--Lymetutu--
Opinions, not medical advice!

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luvmywonderfulkids
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OK, I am very, very confused now. My son Ryan who is 14 now was first diagnosed in Feb. with JRA and then in April with scleroderma, he had a skin biopsy in May which was positive for morphea. After reading everything I could, we opted for the antibiotic protocol from information from the roadback.org website. From there, people told me to get my son tested for Lyme. We did and his results were:

antibody titers:

IFA <1:40 Negative

IGG


31 +

39 IND
41 IND


IGM

41 +
58 +

All others negative.

From this I pushed to do further testing on band 31 because of everything I had read so Igenex performed an entrope test on 31 and it came back positive for chronic lyme.

Am I now going down the wrong path? We have an appointment with Dr. J in CT in December and we are seeing an infectious disease Dr. here at USF in Tampa on Tuesday.

His dermatologist that performed the biopsy feels it makes sense that his problems --morphea and arthralgia were caused by lyme but after reading all these posts, I don't know anymore -- please help!

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CelticLadee
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Just when I thought I was getting the hang of it now I am so confused like a few others in this thread. My recent IgeneX test results are no big deal?

IGM 39 IND, 41++
IGG 31 IND, 34 IND, 41+, 66+

My LLMD told me if I had one more + for a known Lyme antibody he would now say I had LD. I have been chronically ill for 7 + years. LLMD told me the Cpn I was being treated for is a co-infection most likely the LD is my main infection suppressing my immune system.

If we kill the LD won't our immune system take care of all the co-infections then? Do we need to worry about every bug or virus or protozoa swimming around in us?

Next LLMD took me off all my antibiotics for Cpn, after a month is putting me on Biaxin for 3 weeks, then doing a WB IGM test. Would love to here opinions on this... TIA

--------------------
IGeneX WB on 9.09: IGG:31.IND,34.IND,41+,66+
IGM:39IND,41++ on 9.09 same on 1.10
ME/CFS, CPN, EBV, HHV6

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CelticLadee
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Bumping up.

--------------------
IGeneX WB on 9.09: IGG:31.IND,34.IND,41+,66+
IGM:39IND,41++ on 9.09 same on 1.10
ME/CFS, CPN, EBV, HHV6

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LizaLu
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I have EBV and Herpes 6, and the following IgeneX results:

IGG 41 IND

IGM 31 ++
34 IND
39 IND
41 ++
58 +

I'm on month 5 of abx treatment from LLMD. I've seen some progress, but still sick. Today, i found out i'm allergic to cats (have 3). I'm confused now because i've been sick for over 5 years and nearly disabled, having seizure brain activity, nearly narcoleptic, stopped eating and sleeping for years...etc crappy etc

And now i may just have a bad IgeneX test? No i tested neg for co-infects so that mean i probably got no lyme???

I'm a newbie, but Lyme explains a heck of a lot...and don't think i can just be all oh it's just Epstein Bar, allergies, and cold sores.

= )

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Pinelady
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No Liza, you got neuroborreliosis. It is the confirmation test that was being referred to.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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