posted
I'm not a subscriber to his website, but his newsletter states that Lyme is XMRV.
C***** Research Newsletter No. 6
In this issue of the C***** Research Newsletter are posts which interpret the various XMRV tests now commercially available and a post on the inherent problems of easily oxidized oils such as Vitamin E in commercially available nutriceutical preparations. Finally, I explore the relationship of endogenous human retroviruses (ERV's) buried in the human genome and the highly homologous XMRV as it relates to human immunosuppression. The consequences of Th1 suppression and the consequent Th2 up-regualtion by both ERV's and XMRV would appear likely to explain the conundrum of the rise in chronic lyme without apparent overlap with HIV, even in the same endemic areas, and the possibility that XMRV infection is the basis of chronic Lyme.
In this issue:
Interpretation of XMRV Testing Vitamin E preparations - an issue of manufacturing and processing The immunosuppression of ERV's and XMRV - Is XMRV actually chronic Lyme disease?
Interpretation of XMRV Testing Current testing, primarily by VIP Dx in Reno, gives three results. 1) Serum PCR for viral DNA 2) Whole blood PCR for viral DNA and 3) Culture of human blood white cells which amplifies the infection to see it better and the most sensitive of the three tests, the most labor intensive and the most costly. Coming soon will be antibody testing including 4) IgG against a common viral protein and 5) Western blot (WB) which looks at the entire pattern of viral protein antibody expression which are present and considered the gold standard for confirming any direct detection of virus by PCR testing which is subject to false positives. When WB is available, there will likely be a contraction of standard testing to just serum and whole blood PCR and WB if positive to confirm and perhaps WB if negative to confirm any past infection which, of course in a retrovirus, is permanent infection of your DNA. There are other issues involving infectiousness and viral latency that are peculiar to retroviruses. Below is a fuller explanation. Continue reading
Vitamin E preparations - an issue of manufacturing and processing I have tested a patient's response to various vitamin E preparations on the ETM plus a typical array of nutrients that are standard practice in my clinic - Methyl-B12, Hydroxy-B12, Glucose, Fructose, Olive Oil and Fish Oil. The last six always show this kind of response in CFS but not in controls who are all positive for these six except Fructose which can be mixed in controls. CoQ-10 response can be mixed positive or negative in CFS but positive in controls. The historical variance for IVRT testing is plus or minus 1% and IVRT is measured three times and averaged. IVRT is an indirect measure of the free energy in the heart myocardial cells. Positive is good and negative is bad as it indicates a loss of free energy. These immediate responses in IVRT over a few minutes may or may not reflect later effects over time but are rather more useful to detect immediate positive or negative effects. Later effects can also be monitored but requires sequential testing over months of many patients on the same nutrient. This had only been done for a few items we currently use in therapy. Continue reading
The immunosuppression of ERV's and XMRV - Is XMRV actually chronic Lyme disease? Below is an interesting link to a thorough discussion on gammaretroviruses and the related human endogenous retroviruses ERV's of which there are 2,000 ERV genes located on a single human chromosome. There are thousands of ERV's spread across the entire human DNA grouped into 24 families. XMRV has 95% homology with human ERV's. What is very interesting about ERV's and likely true for XMRV is that they are TH1 immunosuppressive which is believed to be critical in the ability to get pregnant as the mother needs to be Th1 immunosuppressed to avoid rejection of the implanted fetus. The hormones of pregnancy and especially progesterone are in part responsible for activating env proteins of ERV's which apparently are largely responsible for this immunosuppression. It is likely that progesterone activates XMRV env protein and may explain why we see women with more CFS at 4 to 1 over men and the apparent vulnerability of adolescent girls to CFS onset and the relative reduction of the point prevalence of CFS in the elderly and in children compared to the young to middle ages. I have also observed a reduction in severity of CFS symptoms in post-menopausal women though perhaps modulated by their use of HRT. The related hormones to progesterone are pregnenolone and cortisol. I have seen both devastate a handful of CFS cases. Continue reading
[ 11-14-2009, 11:17 AM: Message edited by: Anna Lee ]
-------------------- sunnymalibu Posts: 192 | From california | Registered: Jul 2006
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TerryK
Frequent Contributor (5K+ posts)
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posted
Interesting - thanks for posting.
In chronic lyme, there are many possible culprits for th1 suppression. IMO, XMRV is just another one to add to the list that may apply to some people and not to others.
Terry I'm not a doctor
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
Bb takes advantage of our liver enzyme called CYP 350 (MANY variations of that enzyme!).
What that enzyme does is BREAK DOWN things...including fatty acids.
Bb NEEDS fatty acids.
The Cytochrome-P-450 enzymes (CYP) are among the most important xenobiotic-metabolizing enzymes, which
***produce reactive oxygen species (ROS)*** as the result of metabolizing xenobiotics!
Definitions:
Xenobiotics are chemicals in an organism that are not normally present or expected to be there.
"ROS (= reactive oxygen species/''free radicals'' are believed to play important roles in the pathophysiology of autoimmune diseases."
*******
"Rife then began beaming different resonance frequencies on these microorganisms to study the effect.
***In effect, what he found was that bacteria could transform into cancer causing viruses.***
Rife implanted his cancer-causing bacteria into rats. Dr. Rife inoculated 411 lab animals with this virus, created 411 tumors, and then eliminated all 411 of them.
He did the same with many other diseases. From here, Dr. Rife made the startling discovery that the bacteria could change into a completely different form if the "medium on which they were living" was slightly altered."
posted
Hogwash. Even though it is a retrovirus, my guess is that it is one of a SOUP of pathogens we are dealing with.
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lightparfait
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posted
Could retroviruses be activated by environmental chemicals and ingested plastics?
Posts: 1009 | From NJ | Registered: Aug 2009
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AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
If I understand correctly, I think he's saying that he believes that XMRV might cause people infected with Bb to be unable to fight it off, causing them to become chronically infected with Lyme.
Did they find it in ticks or is this infection thought to be a predisposing factor, does anyone know?
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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Thank you for your very interesting post! I love reading your thoughts.
C***** says to stay away from fish oil. I wonder if he's on the same track as you are? He also is a proponent of Artesunate. I feel better when I take daraprim. I wonder if there's a correlation?
[ 11-14-2009, 11:19 AM: Message edited by: Anna Lee ]
-------------------- sunnymalibu Posts: 192 | From california | Registered: Jul 2006
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Tricky 'cause EPA looks to help fight bacteria while DHA looks to help fight viruses that can ultimately trigger cancers.
EPA converts to DHA, but it takes several steps to do so.
Okay...if Dr. Rife was right...if bacteria can convert to much smaller viruses...
that may mean Bb can not only change "his" outer cell wall proteins, go without them (CWD), form cysts which are harder to rid, but also might be able to go "smaller", mutate to a viral form.
Oh, man.
All the more reason for VCO...as it contains acids that are anti-bacterial, anti-fungal AND anti-viral.
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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quote: Okay...if Dr. Rife was right...if bacteria can convert to much smaller viruses...
that may mean Bb can not only change "his" outer cell wall proteins, go without them (CWD), form cysts which are harder to rid, but also might be able to go "smaller", mutate to a viral form.
Ok you gotta stop here now . bacteria does not converts automagically to viruses. period
Or: "Bacterial sporulation: Pole-to-pole protein oscillation"
And it is known that "ultrasound" + abx impacts biofims as well as CWD pathogens.
Rife used that knowledge to cure cancer via very specific frequencies.
Sound waves produce HEAT...that is how our microwave ovens work.
"Streptococcal germs and many other kinds of germs, bacteria and viruses can, and do, change into other forms, proven to occur by many eminent researchers since the early 1800s, including Gaston Naessens, Gunther Enderlein, Royal Rife, Antoine B�champ, and others."
Not unlike others who wrote books about submarines long before they were built.
Others (Gaudi - Barcelona) who designed incredibly strong buildings by mimicing nature ***prior to computer assistance*** (CAD).
Don't shoot the messenger.
P.S. "J Clin Microbiol. 2009 Aug;47(8):2496-501. Epub 2009 Jun 17.
In vitro effect of ultrasound on bacteria and suggested protocol for sonication and diagnosis of prosthetic infections.
"We found that ultrasound had an inhibitory effect on bacteria, of which gram-negative bacteria, in particular Escherichia coli, were almost eradicated after 5 min of sonication at 35 degrees C. Gram-positive bacteria were found to be resistant to the effect of ultrasound."
posted
Marnie what you quoted has no relevance to your previous statement, I am not going to argue any of these as it has no relevance.
Bacteria does not turn into viruses and vice versa -they are completely different entities. bacterias are more or less self sufficient single cell organisms,capable of self reproduction, while viruses are basically just the strands of dna/rna encased in replication package which employ the facilities of cell they infect to reproduce. This is the very basics of microbiology . I am appalled that you are unaware of it
Gene swapping is possible between viruses and bacteria , yet it does not turn one into another
Give us some proof that bacteria can "turn into" viruses.
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D Bergy
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posted
The term "virus" as it was used in Rife's time referred to filterablitly related to the size of the organism.
He very well could have said mycobacteria if such a term existed at the time.
Don't get hung up on the term "virus". Its meaning has changed somewhat since the 1930's. We do not know if it was a virus in today's definition, or mycobacteria.
The point is that he observed pleomorphism of a bacteria into a much smaller forms.
This was the case for Carcinoma, not necessarily all forms of Cancer.
Tuberculosis bacteria released other pathogens when it was destroyed. The released pathogen also had to be destroyed with frequencies or the subject would die from this other pathogen inside the TB bacteria.
He did observe these events in real time. Something no one else has done to my knowledge, although Elmer Nemes had a similar capability. Rife really had no reason to make up a story. He was absolutely anal about repeating these experiments hundreds of times to be sure of his results.
Dan
Posts: 2924 | From Minnesota | Registered: Aug 2006
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posted
I think that XMRV could very well be the reason why Lyme becomes chronic in some and not others.
The "M" is for "Murine" which means mice and rats. It's not uncommon that the tick gets its first meal from those animals...
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Marnie
Frequent Contributor (5K+ posts)
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posted
I am only quoting and linking what I read about what Dr. Rife observed:
Yes...he observed a much smaller form of a bacteria...one that according to him, triggered cancer.
"The origins of viruses in the evolutionary history of life are unclear: some may have evolved from plasmids--pieces of DNA that can move between cells--while
posted
It might be that XMRV causes symptoms of it own too.
I have some symptoms which haven't changed no matter what treatment I have been on. It could be that those symptoms come directly from XMRV.
I will do my best to get tested soon.
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treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Ill say this XMRV is a mouse virus.
What is the first thing ticks feed on ? yeah mice. Now add borrelia in and this retro virus is grabbed or attacks borrelia but low and behold borrelia likes it and absorbs the retro virus rna or dna and wham now the next offspring or bleb uses the capabilities of the XMRV.
tada unrelenting borrelia with better tools inwhich to attack us .
Heck I said this in different words 10 years ago. Borrelia take whatever they can use fron any organism just think of how many animals that borrelia and its ancestors have gone through to get to us?
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
See several entries to this blog -- especially 10/21, 11/03 and 11/11.
I haven't done a lot of research on this new virus yet, but I personally think HHV-6, EBV, CMV and now XMRV could be considered as coinfections -- not sure there is any way to prove which came first -- the borrelia and other tickborne infections or the viruses.
And then don't forget about Borna virus. Wish that got the same ammount of attention. Dr K in Washington thinks all tickborne patients have Borna virus -- at least that is what I read somewhere. Hubby tested positive for that virus 4 times but currently there is no lab in the U.S. which even offers a test. And the main symptoms are neurologic and psychiatric !!!!!!!!!
Bea Seibert
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Pinelady
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posted
Very interesting.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Hoosiers51
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posted
For me, none of it is worth looking into until we know what we can actually do to treat XMRV.
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Pinelady
Frequent Contributor (5K+ posts)
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posted
If it has anything to do with monkeys we don't have
to look any further. But there is an old saying
mice lie and monkeys exaggerate. Change the name,
its still the same.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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