This stuff gets to me cause i did notice after taking probiotics that if felt a good deal better... now i gotta read some article that just claims that because its taking fighter cells from my die off region and surrounding the probiotics to check to see if they are a threat. way to burst my bubble - the probiotic response is only palliative.
-p
-------------------- Bit in March 2005. Posts: 58 | From Jersey | Registered: May 2008
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posted
mmmmm, maybe my LLMD knows something I need to know he has always been against probiotics
Posts: 207 | From NH | Registered: Jul 2009
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
Warning...this is going to get very medically-technical!
"RESULTS: The gut is the major site for induction of regulatory T cells, which secrete immunoregulatory cytokines such as IL-10 and
TGF-beta
and can regulate both Th1 and Th2 responses.
Recent findings suggest that some gut commensals, including lactobacilli, bifidobacteria and helminths, play a major role in the induction of regulatory T cells in gut lymphoid follicles.
Such T cell-mediated regulatory pathways are ***essential homeostatic mechanisms*** by which the host can tolerate the massive burden of innocuous antigens within the gut
TGF-beta acts as an antiproliferative factor (inhibiting cell growth) in normal epithelial cells and at early stages of oncogenesis (malignant transformation).
In other words, TGF beta (secreted by a healthy gut) stops cancer cells from growing.
Trevor...it is UV light, NOT vitamin D that potentiates lyme disease.
Mice, infected with Bb, when exposed to LIGHT -> increased infection.
CB2 receptors + UV light -> inflammation.
Bb NEEDS inflammation to happen.
Why do you think persons who get lyme are given tetracycline which REDUCES inflammation AND are told to stay OUT OF THE SUNLIGHT?
If Bb has a PKCB2 inhibitor which is impacting our T cells, those cells likely are sending to the surface a "call for help", CB2 receptor.
These cells then will become HeLa cells. Immortal.
It appears Bb has a PKCB2 INHIBITOR (which would trigger cell death)...so we counter that!
We thus keep the infected cells alive.
What this will lead to - eventually - is the need for a *man-made PKC inhibitor*, such as tamoxifen.
When and if you gals here need Tamoxifen to destroy breast cancer cells that are immortal (= HeLa)...
This knowledge may save your life:
Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity
Why?
Likewise, the omega-3 fatty acid eicosapentaenoic acid (EPA), which
***inhibits PKC beta II activity ***
and colon carcinogenesis, causes inhibition of Cox-2 protein expression, re-expression of TGF-beta RII, and restoration of TGF-beta1-mediated transcription in RIE/PKC beta II cells.
PMID: 12480928
Keep your gut healthy.
Posts: 9430 | From Sunshine State | Registered: Mar 2001
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Our gut secretes this:
TGF-beta
which
acts as an antiproliferative factor ( = inhibiting cell growth) in normal epithelial cells (these cells make up the epithelium which is a covering of most internal and external organs (our skin is an organ)
and at early stages of oncogenesis (malignant transformation).
"Borrelia burgdorferi bind to *epithelial cell* proteoglycans (glycoproteins - think of them as sugary proteins).
So TGF beta protects us if some cells are heading towards becoming cancerous and it stops the epithelial cells (which Bb attaches to) from growing.
And our gut also secretes IL 10 which is
an anti-inflammatory cytokine.
Our gut helps us control the balance of inflammation and no inflammation.
SOME inflammation is needed to heal. It is when it doesn't shut off that we're in trouble.
It is known that inflammation ...ongoing...is a cancer trigger because it causes "free radicals" which damage our cells.
Does that help?
I'm trying.
Posts: 9430 | From Sunshine State | Registered: Mar 2001
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
Based on the article, It might be better to pulse probiotics. I agree with Marnie and droopy drawers (sorry Ms. TuTu I caught you and TC talking about your animated characters ) you need them but maybe how we're taking them should be discussed more.
Question: Is it better to take probiotics as food and drink versus supplemental?
Question: Is it better to take probiotics ever day, every other day, every third day, etc...?
Here's a thought, our own test -- we get twenty people to test every other day and another group to test every fourth day and run the test for 6 weeks and get some feed back. Another group switch to food/drink orient probiotics 1 every day. I'd bet the results would be very interesting.
I stopped taking supplemental probiotics 6 months ago and haven't missed them. I drink kombucha / I eat sauerkraut -- I've given up on yogurt.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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richedie
Frequent Contributor (1K+ posts)
Member # 14689
posted
Interesting, could it be causing us more harm than good????
We also have no way of knowing our products really have probiotics! They might die in transport...if left in high heat. For this reason I often hear organic yogurt or kefir is best since it must be refrigerated.
Do you know your probiotics contain what they say when you eat them?????
-------------------- Mepron/Zith/Ceftin Doxy/Biaxin/Flagyl pulse. Artemisinin with Doxy/Biaxin. Period of Levaquin and Ceftin. Then Levaquin, Bactrim and Biaxin. Bactrim/Augmentin/Rifampin. Mepron/Biaxin/Artemisinin/Cat's Claw Rifampin/Bactrim/Alinia Plaquenil/Biaxin Posts: 1949 | From Pennsylvania | Registered: Feb 2008
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quote:Originally posted by lymie_in_md: I stopped taking supplemental probiotics 6 months ago and haven't missed them. I drink kombucha / I eat sauerkraut -- I've given up on yogurt.
At least you are doing THAT! To do nothing would be like suicide (for me at least).
I think yogurt is VERY highly overrated. It contains too much sugar...even the plain does.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96227 | From Texas | Registered: Feb 2001
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
I make yogurt and ensure it is fully cultured. No lactose left maybe lactase pre-digested sugar. But I don't think yeast will go after the sugar in that form similar to plant sugar or complex carbs. I've been making my own cultured coconut milk instead. I'll buy some culture starter put it in 32 oz bottle with coconut milk (so delicious - brand) and let it culture for two days in a yogurt maker. I use that in cereal. It's not dairy and relatively simple to make. I'll put that on oat meal in the morning with some other stuff (fresh fruit, dried fruit) whatever.
22 come over for breakfast some time, I'll save you a bowl.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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posted
All I know is at this stage of my treatment my LLMD does NOT want me taking probiotics. I thought it was crazy too...But if I were to post who my LLMD was I bet a lot of you would be surprised and know who he/she was. Very well know.
Posts: 23 | From Southern Maine | Registered: Jun 2009
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) you need them but maybe how we're taking them should be discussed more.
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