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» LymeNet Flash » Questions and Discussion » Medical Questions » BRM4 (MGN3) for NK Cell Activity

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Author Topic: BRM4 (MGN3) for NK Cell Activity
Lymeorsomething
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Has anyone tried this supplement? Another poster mentioned it a week ago. It's supposed to triple NK activity (perhaps raise CD-57). It's expensive though.

It's purportedly backed by studies. I found one below.

Modified arabinoxylan rice bran (MGN3/Biobran) enhances intracellular killing of microbes by human phagocytic cells in vitro.
http://www.ncbi.nlm.nih.gov/pubmed/18336734

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joalo
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Anyone? [confused]

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Sick since January 1985. Misdiagnosed for 20 years. Tested CDC positive October 2005. Treating since April 2006.

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Lymeorsomething
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Zippo? Well, I may try it and I will report back. My CD-57 has been consistently low so I'll know if it does something.

More studies:

http://www.ncbi.nlm.nih.gov/pubmed/19239320

http://www.springerlink.com/content/6m6j41v376u50n06/

http://www.ncbi.nlm.nih.gov/pubmed/15461862

The brand name compound is expensive but there are some cheaper versions by Now Foods and Source Naturals...if you look under~~~>RBAC (Rice Bran Arabinoxylan Compound)

[ 11-18-2009, 01:02 AM: Message edited by: Lymeorsomething ]

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Lymeorsomething
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Ups a daisy [lol]

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coltman
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Thanks for interesting information, albeit it does induce tnf alpha and IL-6 , I am not too sure its a positive thing since it is inflammatory response and it seems in many cases inflammation contributes a lot to damage.

But phagocytosis is important for killing intracellular pathogens (albeit in some studies it shows that even phagocytosis does not destroy some pathogens when cell is killed- they actually just get released into the wild)

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Lymeorsomething
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Yes, very true, Coltman. I was holding out some hope that it may help boost CD-57. Though controversial, I think having low levels may play a small part in relapse, especially if lyme is the essential infectious issue.

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