posted
Curious to know if anyone here has done the Schardt protocol (alternating diflucan and a penicillin) or a similar protocol.
My daughter isn't on the Schardt protocol, but she's been taking diflucan for the past 3-4 weeks (no abx for past 3) and she has had a marked improvement in her functioning (especially increased energy/less fatigue). She's not "healthy" by any standard and has a long way to go, but hasn't been doing this well in a very long time.
Before this, she has been consistently on abx for 1.5 years...mino/plaq, rocephin, numerous other combos. She has taken dozens of supplements (sometimes 30 pills a day!!!) as well, and has always been on nystatin and good probiotics (yet she still got yeast infections). her diet is as good as possible...lower carbs, good protein, lots of veggies, whole grains (challenging with kids).
She is still on a few supplements and just began some homeopathic stuff for lyme and cos. I want her on milk thistle or an equivalent to help support the liver b/c of the diflucan.
So, have any one of you all been on the Schardt protocol, or a variant of it, and what have your experiences been? Did anyone improve? Has anyone been put into remission from this?
Thanks!
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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lymebytes
Frequent Contributor (1K+ posts)
Member # 11830
posted
My next move is to Diflucan. So many good reports from those I know using it.
If you know of the Schardt protocol, you probably have seen this link. If not, check it out, it is a very interesting study of 11 patients that showed much improvement and some cured. There is a "table" of the patients and their main symptoms and what improved just using Diflucan for 25 days. I find the most impressive a man sick with LD for 10 years and neuro symptoms vanish quickly. Several WB also turn IgM negative. All their stories are encouraging for sure, I wish more studies would be done: http://www.daignet.de/site-content/die-daig/fachorgan/2004/ejomr-2005-vol.9/334.pdf
posted
Lymebytes, thanks for that link. I saw the summary version, but not the whole article.
Curious to know what else you've heard about it. I personally can't believe what it's been doing so far for my daughter and we just pray the improvement continues.
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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posted
OOPS! I just posted something very similar. YES
IT WORKED FOR ME!
6.5 weeks unable to walk for the first time as a
LD patient that was nearly miss-dx MS.
200mg a day and on the 3rd day I was up and
going! BUT-I am not the same. I think that I
have neurological damage.
Does anyone ever get better from the damage?
GOOD LUCK! ~John.
Posts: 123 | From Seattle, WA | Registered: Oct 2008
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lymebytes
Frequent Contributor (1K+ posts)
Member # 11830
posted
Ironically, I just had a friend email me and tell me that being on Diflucan has made a big difference for her and she was telling me how I MUST try it. She isn't on the pen/diflucan protocol, but feels best on Zith and Diflucan. I thought I'd pass it on to you.
John I believe anything can heal in our bodies, they are built to heal and constantly trying to restore. Methyl-B12 injections in high doses are excellent for neuro repair. Here is a link with more info: http://www.truthaboutlymedisease.com/phpBB3/viewtopic.php?f=10&t=64
Also from Dr. B's guidelines some info. He mentions 3-6 months, I have had a lot of severe neuro issues, I did the shots at high doses daily for a year and now remain on a high weekly dose: METHYLCOBALAMIN (Methyl B12) Methylcobalamin is a prescription drug derived from vitamin B12. This can help to heal problems with thecentral and peripheral nervous system, improve depressed immune function, and help to restore more normalsleeping patterns. Many patients note improved energy as well. Because the oral form is not absorbed when swallowed or dissolved under the tongue, Methyl B12 must be taken by injection. Dose is generally 25 mg. (1c.c.) daily for 3 to 6 months. Long term studies have never demonstrated any side effects from this drug. However, the urine is expected to turn red shortly after each dose- if the urine is not red, a higher dose may be needed or the present supply may have lost potency. The injectable form of this is not available in regular drug stores. It must be manufactured (compounded) by specialty pharmacies on order.
posted
Diflucan has chemical similarities to metronidazole, expect good blood brain barrier penetration and possible cyst form cidal activity. does alcohol cause problems with this medication. Does it cause neuropathy if taking for several days or weeks?
Antimicrob. Agents Chemother. doi:10.1128/AAC.01263-09 Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.
Effects of Immunomodulatory and Organism-Associated Molecules on the Permeability of an in Vitro Blood Brain Barrier Model to Amphotericin B and Fluconazole By comparison, the BBB model's permeability to fluconazole was >78% in all conditions studied, without significant differences between controls and experimental groups. LPS and TNF decreased tight junction proteins zona occludens 1 (ZO-1) between endothelial cells. In conclusion, IL-1, ZYM and LTA increased BBB permeability to small ions but not to AmB. Whereas TNF and LPS, which disrupted the endothelial layer integrity, increased permeability to AmB.
Better living through chemistry,
Beachinit.
Posts: 448 | From Downeast Maine | Registered: Jul 2009
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posted
Antimicrobial activity of ketoconazole & fluconazole against metronidazole resistance strains of Helicobacter pylori
Abstract number: V1-094P
Siavoshi1 F., Safari1 F., Latifi-Navid2 S., Malekzadeh3 R., Agah4 S.
1Microbiology, Tehran University, Tehran, Iran 2Microbiology, Ardabil Azad, Rdabil, Iran 3Digestive Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran 4Hazrate Rasoul Hospital, Tehran, Iran. E-mail: [email protected]
Ketoconazole and fluconazole as potent antifungal agents are practically inactive against bacteria and most protozoa, in order to search for the more efficacious drugs against H. pylori the antibacterial effects of fluconazole and ketoconazole were assessed against H. pylori isolates, which exhibited either resistance or susceptibility to metronidazole. 35 isolates of H. pylori from patients with digestive disorders were recruited, among them were 11 strains resistant to metronidazole. MICs of ketoconazole and fluconazole for H . pylori isolates were determined by disk diffusion procedure. To examine the effect of ketoconazole and fluconazole on resistance of H. pylori to metronidazole, blood agar plates containing ketoconazole or fluconazole with concentrations below MIC (1/2 MIC), were surface inoculated with bacterial suspension. Blank discs were then deposited on the agar and inoculated with 10 ml of metronidazole (4, 8, and 32 mg/ml). Plates were incubated microaerobically, and examined for the visualization of inhibition zones. All the 35 H. pylori strains were inhibited by ketoconazole and fluconazole. MICs of ketoconazole for 4 and 31 out of 35 strains were determined as 2 mg/ml and 4 mg/ml respectively. All strains were inhibited by fluconazole with the MICs ranging from 2 mg/ml to 8 mg/ml. All the 11 strains which were resistant to metronidazole turned susceptible when treated with ketoconazole and fluconazole in the concentration below MIC. Ketoconazole and floconazole, showed an excellent in vitro activity against the H. pylori isolates. Both antifungals at concentration below MIC (1/2 MIC) converted metronidazole resistant strains to susceptible.
Point being H. pylori mirror Bb for many antibiotic sensitivities. Might just work.
Beachinit
Posts: 448 | From Downeast Maine | Registered: Jul 2009
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posted
Hi neuro, maybe our threads could be connected if possible...since we're both on the same page when it comes to diflucan. LMK what you think.
Lymebytes..thanks for telling me about your friend. I'd like to know more about her story.
Beach...thanks so much for the articles. There's not much out there regarding diflucan.
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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aklnwlf
Frequent Contributor (5K+ posts)
Member # 5960
posted
Interesting.
-------------------- Do not take this as medical advice. This comment is based on opinion and personal experience only.
Alaska Lone Wolf Posts: 6918 | From Columbus, GA | Registered: Jul 2004
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posted
Well if I'd have heard a few years ago that fixing the yeast would help people, I'd have laughed. Ain't laughing now!
Wondering if all the abx people take actually do kill the spirochete but because the abx causes yeast and symptoms from that, people don't notice.
Maybe diflucan or some other anti-fungal is the thing that needs to be prescribed after a few months of abx therapy to finally kill the lyme and the yeast. Nystatin and probiotics are a good thing, but they don't seem to pack the same punch as diflucan.
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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Wondering if all the abx people take actually do kill the spirochete but because the abx causes yeast and symptoms from that, people don't notice.
I've been preaching this for years here. Especially when you are nearing the end of treatment, you need to get serious about treating yeast. Many try to ignore the FACT that yeast and Lyme have VERY similar symptoms.
So... How do you know when you're "cured" of lyme if you have bigtime yeast??? You WON'T know!! You will think you're still ill from lyme ... and MAYBE YOU'RE NOT!!!
OK.. off my little soapbox for now!!
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96239 | From Texas | Registered: Feb 2001
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I've been preaching this for years here. Especially when you are nearing the end of treatment, you need to get serious about treating yeast. Many try to ignore the FACT that yeast and Lyme have VERY similar symptoms.
So... How do you know when you're "cured" of lyme if you have bigtime yeast??? You WON'T know!! You will think you're still ill from lyme ... and MAYBE YOU'RE NOT!!!
OK.. off my little soapbox for now!!
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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I agree. Did you see me standing next to you on the little soapbox??? I was waving to you
Any idea why so few (apparently) remain unaware regarding the role yeast plays in tx?
And people reading this thread, ask yourselves what Lymetoo has asked, and consider whether your sx could be due to LD/Cos or Yeast.
Lymetoo.....been wondering about this for awhile. Can you explain.....
"I am not a doctor, but I DID stay at a Holiday Inn Express!"
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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ukcarry
Frequent Contributor (1K+ posts)
Member # 18147
posted
When I was first diagnosed, I took Diflucan for 3 months alongside Doxycycline: I felt even worse during that time, so can't say that extended Diflucan did much for me.
Posts: 1647 | From UK | Registered: Nov 2008
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posted
Dr. S (the doc who found out it works for LD) states that it will not work if you take an ab at the same time.
Posts: 123 | From Seattle, WA | Registered: Oct 2008
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posted
Hi Neuro, do you know if Dr. S (or anyone else) has published anymore studies on this? I've tried to find more info published in the last few years, but haven't found anything.
UK, Dr. S's protocol is to take diflucan w/o abx, for 50(?) days, then take a basic penicillin for a period of time and go back on the diflucan. Essentially, you rotate the diflucan and penicillin until sx resolve.
Posts: 214 | From where ticks flourish | Registered: Dec 2007
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posted
Neuro, can we somehow combine our threads? Same people are posting on both. Not sure how to do it, but let me know your thoughts.
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