posted
I'm concerned about circulation issues. Here's what's been happening tonight.
I noticed some extra tingling in my foot (I say extra, because I always have a little bit). This seems to be connected with a pulsing, throbbing-like pain -- the kind of pain you feel when blood isn't getting to your hands or feet.
I don't normally feel that when I feel the typical tingling.
As of late, I noticed my veins bulge a little more than usual. And sometimes it's more noticeable when I just stand up; which also gives me a light-headed feeling some days.
Tonight, it all seems to be getting worse. As I lay down, I can feel my hands pulsing and aching softly. I feel my feet doing the same thing, with slight cramps in my legs. I get up, my veins in arms are bulging...same in my feet.
I fell asleep for a half hour, and when I awoke, I noticed by hands looked and felt a little numb like I slept on them, but I didn't.
This all makes me feel like things aren't circulating right in me.
But bottom line, I don't have insurance and cannot afford another hospital visit to find nothing right now.
Can anyone relate to what I'm describing, or am I doomed for another hospital visit?
Is this a good thing? Am I having some kind of die-off?
PLEASE, offer me an opinion.
Here's a list of my current regimen:
Minocycline 100mg once/daily (every other day) Zithromax 600mg once/daily (every other day from Minocycline) Plaquenil 200mg twice/daily
Enzymatic Whole Body Cleanse (14-day program, 1 day left) includes Fiber Milk Thistle Laxative
Olive Leaf Extract (70 drops in water/twice daily) Fish Oil Glucosamine/Chondroitin 1500/1200mg Turmeric Cuturelle Probiotics
Vitamin B-E
Posts: 829 | From MD | Registered: Dec 2009
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IckyTicky
Frequent Contributor (1K+ posts)
Member # 21466
posted
It could very well be dieoff. I have had this many many many times. The bulging blood vessles, tingling, wake up with hands numb as if I'd slept on them etc.
I've gone to the ER for it before and they did nothing for me.
Glad to see you are on Tumeric... helps with the inflammation. It looks like your protocol is probably killing things and you need to detox well.
Be sure you are drinking plenty of water.. LOTS of it. You can add about 8 shakes of sea salt and drink up, it helps.
Just wanted you to know that I've been there..
-------------------- IGM: 18+, 23+, 30+, 31+++, 34+, 39IND, 41++, 58+++, 66+, 83-93IND IGG: 31+, 39IND, 41+ Also positive for Mycoplasma Pneumoniae and RMSF. Whole family of 5 dx with Lyme. Posts: 1014 | From Texas | Registered: Jul 2009
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posted
I am having the falling asleep like feeling in my arms- both, shoulder to fingertips. I kept me up last night off and on. Today, they feel mildy swollen and numb-ish.
Mine was also along with increased urination during the night, which makes me think of excess fluid. I have associated this with my hypothyroidism in the past and my TSH is still too high due to Rifampin.
Posts: 819 | From East Coast | Registered: Apr 2009
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posted
Thanks a lot, for your replies everyone. It helps me accept what is happening.
I managed to get roughly 5 hours of sleep last night, waking up on and off throughout the night.
You ever wake up with mattress marks all over you, like they say you slept too hard? My body is covered in them this morning.
I feel really out of it. Not sure if it's because I only slept 5 hours or my brain isn't receiving blood.
I guess if I can type I'm OK.
I tried the sea salt in water suggestion. I shook the canister 8 times into a glass of water and drank about 20oz of water, and will continue drinking more.
I already drink 6-10 bottles of water daily.
IckyTicky, do you still have to deal with this problem? I have had a less severe form of this problem before, but it feels like it's been getting worse over the past couple weeks.
Posts: 829 | From MD | Registered: Dec 2009
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Did you also have pain in your veins when this happened to you?
It isn't relegated to a particular place, I feel vein throbbing and pain in the legs, the hands, arms, and even my head.
This is scary stuff.
Posts: 829 | From MD | Registered: Dec 2009
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karenl
Frequent Contributor (1K+ posts)
Member # 17753
posted
Wolfed Out,
I have exactly the identical thing. And had the same ideas with blood flow. The minocyclin helped a lot but I only tolerate 50 mg. You also added zithro which could in combination kill cpn. And you added plaquenil which I should only add after three months and only if I tolerate everything well.
So maybe you should just stay on mino for some days. You need to read cpnhelp.org because I think this is what you have, does the vein problems and not lyme.This page is complicated, you need to read everything. I also have it in the bones and heart. I would stop enzymes immediately, they make me totally sick. I do not take tumeric, I think I need the inflammation for healing purposes. Karen
Posts: 1834 | From US | Registered: Oct 2008
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karenl
Frequent Contributor (1K+ posts)
Member # 17753
posted
Forget to ask: do you get little dots or petechia especially on feet or broken blood vessels like spider veins?
Posts: 1834 | From US | Registered: Oct 2008
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Could you share with me the type of pain you feel in your bones and heart?
I'll read through the site.
I do have some spider veins around my ankles, and in the center of my chest that wraps around my left side (around the heart basically). They are faint.
I don't have any petechiae-type rashes.
I've been on Minocycline and Zithromax for over 45 days. I started Plaquenil about 14 days ago.
I've been handling everything fine, and if it wasn't for this, I would running free.
I'm nervous, I haven't been able to get a hold of my doctor and ask if I should take my doses today. I have not taken any medication yet.
Karen, if you believe that's the case, if you were in my shoes would you continue taking your medicine? I know you said just take Minocycline, but today is my Zithromax day. I pulse Zithromax and Minocycline every other day from each other.
Sigh.... More bullsh*t.
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karenl
Frequent Contributor (1K+ posts)
Member # 17753
posted
I without knowing your case and no medical background would take the mino only and stay on mino without pulsing and plaquenil.
The zithro can change the cryptic form to EB form. You have to read the wheldon protocol. If you have transformed too many to EB now it is too much for the mino- only every second day- to kill them off. Then there are too many in the blood and I think you might take only mino to kill all those in the bloodstream and only later on transform more from cryt to EB. Too dangerous now - bloodclots if too many bugs are there.
Take Vit E and fishoil for blood thinning.
I think it is good if this is the reason, there is much hope,better than lyme, but many people have both. I was happy when I found this idea.
Read the Wheldon,.. Heart pain is just sharp pain, bones are vibrating like boiling water and something moving inside. Take care,and read, you might have it.
Posts: 1834 | From US | Registered: Oct 2008
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posted
I need to research on cryptic form to "EB" form. I don't know what "EB" stands for.
So, you think my 600mg of Azithromycin might be too much for my 100mg of Monocycline to handle. What about the Plaquenil?
I'll take the Vitamin E and Fish Oil on your recommendation today. I was going to stop all supplements for one day, but if you think it will help the blood thinning I'll do that.
OK, I'll read the Wheldon.
You should see my "Bartonella" blood smear from Fry Labs. My cells are shaped a little jagged. I was most concerned with their appearance and the possibility that they could cause blood clots.
If you'd like to see it, let me know. I need to send it over to spring for a better interpretation.
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karenl
Frequent Contributor (1K+ posts)
Member # 17753
posted
I think the cryptic is the sleeping form and the EB the elementary body form. Only in EB you can kill it. Stay on blood thinning,1,200 Vit E and at least 3 fishoil.I had a blood clot!
The Azithr can open the cryt and then you have tooooo many floating around, so stop the azitr immediately.
I would stay only on mino every day 100 till things are better. I would stop plaqu. as I have read it makes other things stronger and at the moment you have to slow down.But I never was on plaqu.
I guess your Fry shows hemobartonella, read the post of yesterday. Do you have the biofilm test done. I would love if you discuss it with spring, she is the best. instead of the bartonella I think you have probably the cpn( vein problems). After some days you can treat the fry bug again, just now something was too much.
I got in serious trouble last year when I added coptis and did not know that it can open the cryptic form and I was on no antibiotic at all.
The wheldon would only add azitro if mino is well tolerated and then I think not this relation. I plan taking plaquenil not at the same time as killing cpn, but I am afraid of plaquenil.
Compare this to Wheldon: 600mg of Azithromycin might be too much for my 100mg of Monocycline
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posted
Plaquenil could actually be causing neuropathy along with the stabbing of lancinatin type nerve pain.Final Diagnosis -- Toxic Polyneuropathy Induced by Hydrochloroquine
FINAL DIAGNOSIS: TOXIC POLYNEUROPATHY INDUCED BY HYDROCHLOROQUINE
DISCUSSION:
Because of the complexity of the medical history of this patient, the differential diagnosis from the clinician's point of view included the vasculitides of collagen vascular disease, polyneuropathies associated with paraproteinemia, and iatrogenic causes. Chloroquine (together with Perhexiline maleate and Amiodarone) is an amphiphilic drug known to cause lipidosis both in animals and in humans (1,2,3) . The drug or its compounds interact with anionic groups of acidic phospholipids of cellular membranes forming a complex that is not diggested by lysosomes and is rearranged into concentric lamellar or crystaloid myeloid bodies. Complications of chloroquine when used in the treatment and prevention of malaria and in the treatment of connective tissue disorders include a vacuolar myopathy and sensory motor polyneuropathy. The development of chloroquine neuromyopathy may occur from several months (3) to several years (1) post-treatment. In nerve biopsy, the changes include segmental demyelination, axonal degeneration and the accumulation of pleomorphic osmophilic bodies with two distinct profiles; lamellar and curvilinear. They occur in the schwann cell cytoplasm, in perineural cells, in endothelial cells and smooth muscle cells but not in axons. The diagnosis of chloroquine neurotoxicity can be suspected by light microscopy, the inclusions being readily detected under oil immersion microscopy of semithin resin sections. In our patient, although the cause of neuropathy is probably multifactorial, the histology favors chloroquine neurotoxicity as significant pathogenesis of peripheral nerve dysfunction. Although some authors believe that chloroquine neuropathy is caused by primary involvement of schwann cells (1), in many cases a significant axonal component has been found, probably caused by degeneration of spinal ganglia neurons.
REFERENCES:
Tegner R, Tome FM, Godeau P, Lhermitte F, Fardeau M: Morphological study of peripheral nerve changes induced by chloroquine treatment. Acta Neuropath 75:253-260, 1988. Estes ML, Ewing-Wilson D, Chou SM, et al: Chloroquine neuromyotoxicity. Clinical and pathogenic perspective. Am Jour Med 82:447-455, 1987. Leger JM, Pnifoulloux H, Dancea S, Hauw JJ, Bouche P, Rougemont D, Lapane D: Neuromyopathies a la chloroquine: 4 cas a cours d'une prophylaxie anti-paludeene. Revue Neurologique 142:745-752, 1986. Contributed by Juan M. Bilbao, MD, FRCP(C
I could not take quinolones due to severe anxiety type reaction also a nervous system effect. I think the zithro and mino is a good combination but you may want to cut zithro in half say 4 out of 5 days if getting too much GI or stomach upset.
If you still need a 3 rd drug you could add flagyl/tinda or Bactrim (if Bart is problem though others use rifampin)
Beachinit.
-------------------- Ideas not advice. Posts: 448 | From Downeast Maine | Registered: Jul 2009
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