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» LymeNet Flash » Questions and Discussion » Medical Questions » Anyone have an elevated protein level in CSF (Spinal Tap)?

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Author Topic: Anyone have an elevated protein level in CSF (Spinal Tap)?
alextaylor14
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I had a spinal tap done a while back for MS and other things.

They tested for lyme in my CSF also and it came back negative which bothers me....

But the only thing that was out of range was my protein level was high...

Anyone have this?

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carly
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I had one done awhile back. It was not tested for lyme.

The protein level was high. That left the doctors scratching their heads.

The bacteria level was slighly elevated, I think less than one or two hundred, I don't remember the exact number.

Again, a head-scratcher. Normal is close to zero, while a bacterial infection is in the thousands.
A viral infection would be close to zero bacteria also.

But, to answer your question- yes.

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alextaylor14
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Yeah mine was 46 and the range was 1-45. I wonder if its indicative of something.
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seibertneurolyme
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Hubby had 3 spinal taps early in his illness. The 2nd one when he was unconscious for 15 hours and had symptoms of encephalopathy showed elevated protein. I think the number was 46 for him but it is hard to remember as this was in 2002. Anyway when he finally got to a Lyme neurologist a year or so later, the elevated protein was one of the reasons the neuro put him on IV Rocephin -- his first antibiotic.

The spinal fluid was negative for Lyme from the University hospital lab, but after he got out of the hospital we got test results back from IgeneX which showed a positive PCR for Lyme -- this was from bloodwork done a week or so before the hospital admission. Western Blots were totally negative for all bands.

Bea Seibert

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alextaylor14
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seilbertneurolyme- I had my spinal tap done around November of last year when we were worried about MS. The only thing that was elevated was the protien levels. Fast forward to now I have seen two ALS specialists both have said I dont have ALS. Just within the last week I have developed severe brain fog(which has been very mild before) fatigue and burning skin to go along with my weak leg.

[ 10-09-2010, 03:21 AM: Message edited by: alextaylor14 ]

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bigstan
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Without a doubt. Elevated protein high indicator of Lyme disease.

This was the clincher that was decided with my infectious disease doctor that I did indeed have chronic Lyme.

Having the availability to look at the best medical books I did some research and showed my doctor this following paragraph:

"Cebrospinal fluid usually shows a mild to moderate mononuclear pleocytosis {usually <500 cells}, and or moderately elevated protein and normal glucose concentrations."

Spinal test, best test ever for me and I had many tests.

--------------------
HERX is a Four Letter Word!

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Carol in PA
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Cerebrospinal Fluid Analysis

Protein Level
CSF protein concentration is one of the most sensitive indicators of pathology within the CNS.

Elevated CSF protein is seen in infections, intracranial hemorrhages, multiple sclerosis, Guillain Barr� syndrome, malignancies, some endocrine abnormalities, certain medication use, and a variety of inflammatory conditions.

Source:
http://www.aafp.org/afp/2003/0915/p1103.html


Does that help?
Carol

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