LymeNet Flash: IgG subclasses 1-4 HELP w/ interpretation

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»	LymeNet Flash » Questions and Discussion » Medical Questions » IgG subclasses 1-4 HELP w/ interpretation

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Topic: IgG subclasses 1-4 HELP w/ interpretation

feelfit
Frequent Contributor (1K+ posts)
Member # 12770

posted

Recently tested, my results:

IgG Subclasses 1-4

subclass 1= 405 low range= 422-1292
subclass 2= 405 range= 117-747
subclass 3= 26 low range= 41-129
subclass 4= 14 range= 1 -291

anyone know anything about these and what this means? obviously my 1 and 3 are not up to par...

what exactly is this measuring? Immune system, right? is it a sign of autoimmunity?

Thanks in advance for any help,
Feelfit

Posts: 3975 | From usa | Registered: Aug 2007 | IP: Logged |

susank
Frequent Contributor (1K+ posts)
Member # 22150

posted

Did they test for total IGG serum?

I'm dealing with the same thing - waiting to hear back from doctor in regards to IVIG.
Actually hoping Vivaglobin instead of IV.

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009 | IP: Logged |

Michael_Venice
LymeNet Contributor
Member # 17254

posted

I had very similar test results PRIOR to getting diagnosed with lyme, etc.--when I got sick and was going from doctor to doctor. UCLA thought I had a subclass deficiency...though, the most hallmark symptom of it is near-constant upper respiratory infections (which I never had...I had 'lyme' type symptoms). Also, usually long-standing problems with infection, which I also did not have.

However, they seemed sure...my insurance denied IVIG, despite 2 letters from the head of immunology at UCLA. I appealed to the state, denied. I paid out of pocket for IVIG...it didn't help me. It was kind of awful, I had a crazy headache, and then got a rash on my hands that looked like leprosy or something for about 6 weeks.

I had no relief, and the docs at UCLA said they guessed I did NOT have a subclass deficiency illness..and, er, suggested physical therapy instead. Quite a leap.

Anyway, I've read where others here have had similar numbers. Mine haven't been looked at in well over a year, but came up low-ish, like yours, a number of times.

Posts: 322 | From Venice, CA | Registered: Sep 2008 | IP: Logged |

seekhelp
Frequent Contributor (5K+ posts)
Member # 15067

posted

Feelfit, I have the same as you on subclass 1. As you know, my docs thought little to nothing of it. Michael's interpretation is accurate.

Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008 | IP: Logged |

CD57
Frequent Contributor (1K+ posts)
Member # 11749

posted

Physical therapy? On what?

Posts: 3528 | From US | Registered: Apr 2007 | IP: Logged |

feelfit
Frequent Contributor (1K+ posts)
Member # 12770

posted

SusanA, i think they tested for IgA ttl serum (normal)

Thank you everyone for your responses..and to chuckG for the excellent link...much appreciated.

My doctor has not commented on these results (LLMD) and my PCP did not even know how to interpret the results....at least she was honest [Smile]

Posts: 3975 | From usa | Registered: Aug 2007 | IP: Logged |

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