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» LymeNet Flash » Questions and Discussion » Medical Questions » Advice on starting on Zithro

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Author Topic: Advice on starting on Zithro
JS in OK
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I had my first visit in Aug with Dr C. He started me on clinda/quinine for 10 days and rotate to Biaxin/plaquenil for 10. I did a round of both but was sick more than not. I could not tolerate the quinine at all! My ears rang so bad after just 2 days of 1 a day. I called and they said stop all and start Zithro 250mg 2x day. What do I need to know about this drug? I decided to take a few days off before starting it.
Posts: 39 | From Oklahoma | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
janet thomas
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I wouldn't be too worried, I doubt zithro will hit you like quinine did.

You should read the wikipedia article on quinine-very difficult to tolerate.

This was posted a while ago but i found it informative:


Rianna
Frequent Contributor (1K+ posts)
Member # 11038

posted 09 January, 2009 05:53 AM
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Hi Jay,

My LLMD wants me to start this right away SCARY MARY

He said he has had very very good response with Primaquine when used with Clindamycin/quinine, he said as long as its not used as monotherapy its excellent.

trouble is I cant get it here in the UK so will have to try Spain/USA - any ideas anyone?

Thanks
Rianna
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I am not a doctor and this is not medical advice but only my personal experience and opinion.

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seekhelp
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JS, that first protocol sure sounds familiar. The good ole' Dr. C Babs treatment. [Smile] I too struggled with Quinine and the dosing used is baby amounts compared to IDSA recommendations, BUT the duration is longer i believe. In general, it's a hard drug. Didn't do anything for me for Babesia. Too short of a treatment. [Frown]

I think you'll have Zith better at the doses used.

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JS in OK
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thanks, I feel better hearing that "seekhelp".
Posts: 39 | From Oklahoma | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
   

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