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» LymeNet Flash » Questions and Discussion » General Support » Bullous Pemphigoid

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Author Topic: Bullous Pemphigoid
dontlikeliver
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Is there a link between this and Lyme?

I am asking because a family member, aged 66 with a several decades long history of schizophrenia (following meningitis aged 7) and progressive undefined physical illness, has now developed this skin disease, Bullous Pemphigoid.

I do not believe that every sick person has Lyme, but I do wonder in her case whether her "meningitis" in 1945 might have been Lyme meningitis. It left her paralyzed for several months and was followed by hallucinations which later in life turned to Schizophrenia.



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tabbytamer
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There are so many viruses and bacteria that go undetected and eventually get at the brain.

I know what you mean, though, you don't believe Lyme is the cause of everything but at the same time, it certainly should be looked into.

Have you tried doing a Google search for "Bullous Pemphigoid causes" or something similar?

Sorry I couldn't be of help. Maybe someone else has some ideas?

------------------
Tabby


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dontlikeliver
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Hi,
Yes, I googled it and it seems related to things like Lupus, RA, but no mention of Lyme.

DLL


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CA quest
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Did a quick search. Found this...sounds like neurological disorders have a strong correlation with BP(BP=bullous Pemphigoid). Lyme is a neurological disorder. Quest


Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.


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Ann-OH
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http://www.hmc.psu.edu/healthinfo/b/bullouspemphigoid.htm is a great discussion of the problem

And this site says uticaria is hives) http://www.utmb.edu/otoref/Grnds/derm.htm

"Erythema chronicum migrans (Lyme disease) is caused by Borrelia burgdorferi from a tick bite. The incubation period is 3 - 32 days. There are usually mild symptoms including headaches, fever, and aching. The skin lesion is a red macule that expands peripherally and clears centrally that develops at the site of the bite. Secondary lesions include blotchy erythema, annular plaques, malar rashes, or urticaria."

Hope this is helpful.

Ann - OH


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Ann-OH
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Wow, how did that little blue-faced guy get in there? I didn't do that!

Ann - OH


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dontlikeliver
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Thanks a lot. And, thanks for the links. It's not impossible then that it is possibly Lyme related, assuming her mental illness is caused by Borrelia. (not to mention her unexplained inability to walk).

DLL


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Linda LD
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There is a doctor in Penn. Dr. S who is WONDERFUL!!!

Email me and I will send you her phone number. I believe she would say yes!

Linda


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dontlikeliver
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Hi Linda,

Did you mean this for me, or for another post?

DLL


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