Drugmakers are uniting together to create one large database that will include results of failed Alzheimer's disease drug studies.
The database was launched on Friday, and contains information from 11 studies.
More than 4,000 files of patient information will be available for researchers to examine and analyze. The information will provide new insight about the disease and how to go about treating it.
The information will be available to independent researchers, not only big name drug manufacturers.
I hope someone dives in and shows them the err of their ways.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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Moving to General Support.
Posts: 89 | From U.S. | Registered: Apr 2010
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Pinelady
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For the life of me I cannot figure out how this belongs in GSupport.
Alzheimers is being misdiagnosed as Dr. McD has so eloquently explained in findings of spirochetes in deceased A. patients brains...
Herein is further evidence that I believe should be in medical where other researchers may be interested.
As well as Advocates who can use the information to get patients appropriate medical treatment...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831066/?log%24=activity Published online 2010 March 3 AMPs, including LL-37 [21], can be bacteriostatic or bactericidal depending on peptide concentration, ionic strength, and the type of stressor a colony has previously encountered.
However, a re-evaluation of the role of Aβ in inflammation may now be warranted in view of
these data suggesting that the peptide functions as an AMP in tissues.
In a second potential pathogenic mechanism, a transient infection may lead to a self-perpetuating innate immune response.
Transient triggers may include pathogens reported to be present in AD brain.
And in a third mechanism, an inappropriate inflammatory response by the innate immune system to transient or persistent non-infectious insults could also trigger a self-perpetuating innate immune response.
While dozens of diseases have been suggested to involve immune abnormalities, for most, the underlying cause of the aberrant immunoresponse remains unclear.
For AD, traumatic brain injury [71], stroke [72] and certain forms of inhalant anesthetics [73] have been linked to increased cerebral Aβ levels. Thus, while an infection-mediated pathological mechanism for AD is certainly one possibility for triggering an innate immune response in the CNS and subsequent production of antimicrobially active Aβ, other non-microbial factors may also be involved.
Interestingly, peptides containing the microtubule binding sites on tau proteins have also been shown to harbor antimicrobial properties ------------------------- If we don't do something to get the info to the doctors who treat, including psychiatrists, and geriatrics who can conduct trials--nothing will change.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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-------------------- sixgoofykids.blogspot.com Posts: 13449 | From Ohio | Registered: Feb 2007
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This IS MAJOR Medical info we ALL need to know!
quote:Originally posted by Pinelady: Alzheimer's is being misdiagnosed as Dr. McD has so eloquently explained in findings of spirochetes in deceased A. patients brains...
------------------------- If we don't do something to get the info to the doctors who treat, including psychiatrists, and geriatrics who can conduct trials--nothing will change.
Pinelady is quite right for the most part, but i beg to differ on her closing phrase.
Things ARE changing! Thousands more get LD & co's every week because no mega media blitz is explaining the risks of these horrific infectious diseases. Soon, there will be just TOO many Americans sick with LD for us (seeking remission now) to care for them in any adequate way.
Ya' think some convalescent homes are unpleasant now?
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