TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
I think I have this right. It appears that protozoans, certain ones at least, need niacin to survive and reproduce. And they cannibalize YOUR niacin. So, does that mean you feed protozoans if you supplement with niacin? Possibly.
There are some interesting details for those that can follow it. Perhaps only people like Marnie could fully understand this. It's somewhat over my head.
"Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum"
Citation: O’Hara JK, Kerwin LJ, Cobbold SA, Tai J, Bedell TA, et al. (2014) Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum. PLoS ONE 9(4): e94061. doi:10.1371/journal.pone.0094061
poppy
Frequent Contributor (1K+ posts)
Member # 5355
posted
Every time they find that some pathogen requires a nutrient, this seems to be the answer. The problem is ALWAYS that these nutrients are required by humans too, so you can't starve them out without hurting yourself. Parasites get that name for a reason. They can't make all this stuff themselves, so they get it from us. Parasities in the broadest sense.
Posts: 2888 | From USA | Registered: Mar 2004
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TNT
Frequent Contributor (1K+ posts)
Member # 42349
posted
True, we can't stop eating or supplementing because our bodies need nutrients to survive, too.
But I do remember taking higher dose niacin a couple years ago and it just seemed to get less and less effective for me. I always wondered what was going on. This could have been part of it.
Posts: 1308 | From Eastern USA | Registered: Oct 2013
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Most nutritional supplements - especially in large doses - become less effective over time. When you are actually deficient in a nutrient often you can notice that some symptom improves but as time goes on your body builds up reserves for many nutrients so it becomes less effective.
For example the body stores up to 5 years worth of vitamin B12. Fat soluble vitamins can actually be overdosed because they are stored. The water soluble ones (most b vitamins and also c) are excreted daily for the most part.
Minerals are stored in bones mostly I think.
Bea Seibert
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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posted
A while back I did a detox regimen that involved taking increasing amounts of niacin. In that niacin supposedly can burn out some of the other vitamins I was also taking increasing amounts of vitamins and minerals.
I went from 100 mg to 5000mg over a about 3 week period while sweating long periods in a sauna. At the end there was absolutely no response to the niacin i.e. no flushing.
I have done it 3 times over the last 30 years and thinking about doing it again. I have never felt so clean. OK, I'll redo it once I get over my hot temperature sensitivity.
Be Well 1 Flew Over
Posts: 4 | From Left Coast U.S. | Registered: Feb 2015
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