posted
Thanks David ! I've been looking for an alternative treatment for Babesia as I developed severe itching from Mepron, (Poss allergy ?). Al
Posts: 789 | From CT, | Registered: Jun 2006
| IP: Logged |
posted
I was just about to say the cost of babesiosis treatment isn't bad - I took clindamyacin and quinine. Had doxy before and after this combo. I don't remember if I ever did zith. Sigh. Maybe.
Posts: 731 | From NH | Registered: Jan 2002
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
Differential efficacy of drug combinations in the elimination of Babesia infection in humans Combination of drugs Daily dosage (mg) Weeks after treatment Babesia detected in patient by Giemsa-stained blood smears Hamster inoculation
Combination A Clindamycin plus quinine-- Daily Dosage Clindamycin 1200mg quinine 1950mg Weeks 2=positive 4=pos 8=pos 12=pos
Combination B Azithromycin plus quinine Daily Dosage Azithromycin 1000mg, Quinine 1950mg Weeks 2=Negative 4=Neg 8=Neg 12=Neg
A 10-day course of therapy with combination A was given and combination B was administered for another 10 consecutive days two months after initial treatment, and hamsters inoculated with 1 ml of the patient's blood were used to verify the clearance of babesial infection.
Looks like that cured it? Camp B wins combination B !!!!
Department of Parasitology and Tropical Medicine,National Defense Medical Center, Taipei,Taiwan, Republic of China: Department of Pediatrics, Tri-Service General Hospital, Taipei,Taiwan, Republic of China
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
I never took mepron either. Cleared it with clindamycin/quinine and artemisinin.
My doctor has stats on HIS patients who have been treated with clindy/Q or mepron/zith. He has about a 5% better result with clindy/Q!!
Thanks for the link, david.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
up
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
| IP: Logged |
CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
posted
With tissue stage Babesiosis- which WA1 is but not Microti I believe (could be wrong here- correct me if I am!*) Malarone is a better choice!!! Better tissue penetration thahn Mepron- was a paper on it years back-
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
| IP: Logged |
quote:Originally posted by CaliforniaLyme: With tissue stage Babesiosis- which WA1 is but not Microti I believe (could be wrong here- correct me if I am!*) Malarone is a better choice!!! Better tissue penetration thahn Mepron- was a paper on it years back-
How does that compare to the combo of Azithromycin plus quinine?
Posts: 310 | From TN | Registered: Jan 2007
| IP: Logged |
oxygenbabe
Frequent Contributor (1K+ posts)
Member # 5831
I can't recall-is quinine hard on the system, or was it clindamycin? If its the latter, this might be a good regimen. But how many days? Plus on giemsa smear my babesia doesn't show up but its positive on FISH. So, I don't know how I'd re-test, I guess FISH.
Posts: 2276 | From united states | Registered: Jun 2004
| IP: Logged |
Boomerang
Frequent Contributor (1K+ posts)
Member # 7979
posted
I don't know the answers, but hubby is on Clindamycin/quinine combo now. Sounds like his stomach is about to erupt.
Posts: 1366 | From Southeast | Registered: Sep 2005
| IP: Logged |
bpeck
Frequent Contributor (1K+ posts)
Member # 3235
posted
Excellent article... Read the last page on immunocompromised patients w/Babs.. interesting.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
quote:Originally posted by treepatrol: Differential efficacy of drug combinations in the elimination of Babesia infection in humans Combination of drugs Daily dosage (mg) Weeks after treatment Babesia detected in patient by Giemsa-stained blood smears Hamster inoculation
Combination A Clindamycin plus quinine-- Daily Dosage Clindamycin 1200mg quinine 1950mg Weeks 2=positive 4=pos 8=pos 12=pos
Combination B Azithromycin plus quinine Daily Dosage Azithromycin 1000mg, Quinine 1950mg Weeks 2=Negative 4=Neg 8=Neg 12=Neg
A 10-day course of therapy with combination A was given and combination B was administered for another 10 consecutive days two months after initial treatment, and hamsters inoculated with 1 ml of the patient's blood were used to verify the clearance of babesial infection.
Looks like that cured it? Camp B wins combination B !!!!
Department of Parasitology and Tropical Medicine,National Defense Medical Center, Taipei,Taiwan, Republic of China: Department of Pediatrics, Tri-Service General Hospital, Taipei,Taiwan, Republic of China
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
posted
Thanks for posting this! Good to know of other options apart from Mepron and Malarone.
Posts: 261 | From Herx-ville!! | Registered: Aug 2006
| IP: Logged |
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
quote:Originally posted by ElaineC: Thanks for posting this! Good to know of other options apart from Mepron and Malarone.
Yep no problem all this stuff is also free for te reading in Newbie links
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
upsy
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:
The
Lyme Disease Network of New Jersey 907 Pebble Creek Court,
Pennington,
NJ08534USA http://www.lymenet.org/
UBBFriend: Email this page to someone!
![[Smile]](smile.gif)
![[Big Grin]](biggrin.gif)
Printer-friendly view of this topic