Topic: NO Doxycyline with Mepron and Azithromycin when treating for Babesia says this LLMD
Health
Frequent Contributor (1K+ posts)
Member # 6034
posted
I am sure some of you have seen this slide presentation, I had it saved on my Favourites list on my computer and just happened to view it today by accident when looking for something else.
GLAD, I did, because I am to be on Mepron and Azithromycin I think if all goes well, and Dr B says, NO Doxycycline! when on this combo, and I am wondering if this also means Minocycline as well.
Here is the slide I am talking about, and some of you I read on here are or were on Doxycyline with Mepron and Azithromycin,
posted
Tetracycline antibiotics (including doxycycline and minocycline) interacts with mepron/malarone, making mepron/melarone less efffective.
However, a doctor may still prescribe doxy or mino with mepron if they are treating other co-infections, such as ehrlichia for which zithromax is fairly ineffective.
Posts: 187 | From Washington, DC | Registered: Dec 2004
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TerryK
Frequent Contributor (5K+ posts)
Member # 8552
posted
Another member and I both called the manufacturer about doxy and mepron. I talked to the pharmacist there and she said it can reduce mepron by up to a whopping 40%!!
Terry
Posts: 6286 | From Oregon | Registered: Jan 2006
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posted
This does concern me as I'm on Malarone and Mino. However, I know the Malarone is working as it's alleviating my symptoms and I'm only taking one per day, plus it caused one heck of a herx when I started back on it.
I asked my LLMD about it, and he said he has had good luck with these combinations .... though I can't say it doesn't still concern me.
-------------------- sixgoofykids.blogspot.com Posts: 13449 | From Ohio | Registered: Feb 2007
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AliG
Frequent Contributor (1K+ posts)
Member # 9734
posted
Hey Terry!
Was that me, you were referring to?
Not only did I give GSK heck for reporting the interaction under Malarone, but not Mepron, when it occurs with the Atovaquone (NOT the proguanil), I also reported the "oversight" to the FDA.
GSK's "scientific research dept" confirmed that it was INDEED with the atovoquone & could give no good reason for the omission from the Rx info, only that they probably found out about it AFTER it was written.
I wonder if they've done anything about it yet. I doubt it, having people "waste" such an expensive med must result in quite a pretty bonus for them.
-------------------- Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner. Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006
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luvs2ride
Frequent Contributor (1K+ posts)
Member # 8090
posted
I remember reading under Zithromax's information not to take it with a tetracycline class med.
Luvs
-------------------- When the Power of Love overcomes the Love of Power, there will be Peace. Posts: 3038 | From america | Registered: Oct 2005
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-I was already on Malarone, Zith and Art for Babs and my LLMD suggested adding Doxy.
I had read all the literature saying not to take the two together, and brought it to the attention of my LLMD - sent him DETAILED links etc. from Dr.'s B and S and the GSK website.
He is a very well-known and respected LLMD in Upstate NY with alot of Babs experience, and he assured me that he has been using this combo for many many years and in his experience, it works well when used with Zith.
Sixgoofykids - I think I remember you saying you had amazing results on this....as had others in the link below.
I guess, like everything Lyme-related, it may be individual though.
I did this for 3 months and have now stopped it, and added Septra and Lariam to an increased dose of Malarone and Art instead. Hard to say if the Doxy was interfering - maybe my babs treatment wasn't aggressive enough anyway.
Would be interesting to do do a poll on this!
Posts: 261 | From Herx-ville!! | Registered: Aug 2006
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posted
I personally experienced this in the recent past - was on mepron, zith and mino.
It seems that the mepron and the mino cancelled each other out - it seemed to work both ways. It is a long story of how I realized it, but it was through trial and error until I went off the mino and then the mepron started to work.
A short while later, I was informed by somebody on this group that the tetras can reduce the effectiveness of mepron by about 40%, as you said.
Now my babs treatment is starting to work - now that I am off the mino.
The mepron also cancelled out the dizziness side effects of the mino - and when I went off the mepron while still on the mino, the dizziness got so bad and turned into seizurey activity.
Now, maybe this is a side effect of the mino, or maybe the mino then started to cause a herx because it only became effective when I went off the mepron.
I told my LLMD that I thought they were cancelling each other out and he thought it was interesting. I then gave him the info on the tetras counteracting the mepron.
Good post and important info!
Posts: 588 | From Rhode Island | Registered: Jun 2006
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